2-Fluoro-5-(1-(methoxycarbonyl)cyclopropyl)phenylboronic acid CAS 2377608-18-7
| CAS No. | 2377608-18-7 |
| Molecular Formula | C11H12BFO4 |
| Molecular Weight | 238.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-5-(1-(methoxycarbonyl)cyclopropyl)phenylboronic acid.
CATO supplies 2-Fluoro-5-(1-(methoxycarbonyl)cyclopropyl)phenylboronic acid (CAS 2377608-18-7), a certified reference material (molecular formula C11H12BFO4, MW 238.02 g/mol) for analytical method development and quality control.
2-Fluoro-5-(1-(methoxycarbonyl)cyclopropyl)phenylboronic acid (C11H12BFO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12BFO4 |
| Molecular Weight | 238.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Fluoro Standards
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- 2-FLUORO-6-IODOPYRIDIN-3-AMINE (CAS 1422443-52-4)
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Recommended Standards
- (1R,5R)-1-(Iodomethyl)-3-oxabicyclo[3.1.0]hexan-2-one (CAS 2574634-45-8)
- 3-hydroxy-2-iodocyclohex-2-en-1-one (CAS 642088-17-3)
- (E)-5-(2-Ethoxycarbonylethen-1-yl)-2-fluorophenylboronic acid (CAS 1855897-91-4)
- 3-iodobicyclo[1.1.1]pentane-1-carboxylic acid (CAS 224584-16-1)
- 2-(3-Amino-1h-1,2,4-triazol-1-yl)-N-cyclopentylacetamide (CAS 1183991-01-6)
- (1-Propylpyrrolidin-3-yl)methanamine (CAS 959239-12-4)
- 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-oxobutanoic acid (CAS 491831-88-0)
- N-(4-Butoxyphenyl)hydrazinecarbothioamide (CAS 1263377-12-3)
- 4-Amino-1-ethyl-1,2-dihydropyridin-2-one hydrochloride (CAS 1523618-09-8)
- 6-((Trifluoromethyl)thio)pyridin-3-amine (CAS 1153767-25-9)
- Trenbolone Impurity 2 (CAS 53303-85-8)
- 7-Methoxy-1H-benzo[d][1,3]oxazin-2(4H)-one (CAS 1187195-69-2)
- 2-(Acetamido)benzothiazole-6-boronic acid pinacol ester, 97% (CAS 885069-14-7)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
Why CATO?
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