(6-Chloro-2H-1,3-benzodioxol-5-yl)boronic acid CAS 2377608-88-1
| CAS No. | 2377608-88-1 |
| Molecular Formula | C7H6BClO4 |
| Molecular Weight | 200.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (6-Chloro-2H-1,3-benzodioxol-5-yl)boronic acid.
(6-Chloro-2H-1,3-benzodioxol-5-yl)boronic acid (CAS 2377608-88-1), molecular formula C7H6BClO4 and molecular weight 200.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (6-Chloro-2H-1,3-benzodioxol-5-yl)boronic acid (C7H6BClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (6-Chloro-2H-1,3-benzodioxol-5-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BClO4 |
| Molecular Weight | 200.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-Chloro-6-(dihydroxyboranyl)benzoic acid (CAS 1838186-55-2)
- 2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane (CAS 718641-97-5)
- 3-Chloro-4-methoxy-5-methylphenylboronic acid (CAS 1050509-76-6)
- (4-Chloro-2-(methoxymethyl)phenyl)boronic acid (CAS 1208318-89-1)
- 2-Chloro-3-ethoxyphenylboronic acid (CAS 1256345-57-9)
- (3-Chloro-5-ethoxyphenyl)boronic acid (CAS 1256345-73-9)
- (4-Chloro-3-(methoxymethyl)phenyl)boronic acid (CAS 1392415-54-1)
- 2-Chloro-5-methoxymethylphenylboronic acid (CAS 1451392-23-6)
Recommended Standards
- (5-Chlorobenzo[d][1,3]dioxol-4-yl)boronic acid (CAS 2087452-50-2)
- 2-Borono-4-chlorobenzoic acid (CAS 874290-67-2)
- 2-Borono-5-chlorobenzoic acid (CAS 850568-07-9)
- 4-Borono-2-chlorobenzoic acid (CAS 136496-72-5)
- 1-(3-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1082437-10-2)
- 2-(4-oxocyclohexyl)acetic acid (CAS 52263-23-7)
- 4-(Benzenesulfonyl)-5-(4-chlorophenyl)-1-phenyl-1H-pyrazole (CAS 318951-61-0)
- Phomalone (CAS 159768-89-5)
- 1-(tert-Butoxycarbonyl)piperidine-2,4-dicarboxylic acid (CAS 1922699-61-3)
- Flurbiprofen Impurity 173 (CAS CATO-C4X-1444173)
- 2-(2-Methyl-5-nitro-1h-imidazol-1-yl)ethyl carbamate (CAS 31478-45-2)
- 6-(N-(4-Ethylphenyl)sulfamoyl)-N-(2-methylcyclohexyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (CAS 901045-74-7)
- 2-Ethyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid (CAS 854405-79-1)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
Why CATO?
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