2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane CAS 718641-97-5

Purity 97%+In StockPharmaceutical Standards
CAS No.718641-97-5
Molecular FormulaC8H7BClFO2
Molecular Weight200.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane CAS 718641-97-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 200.40 g/mol gives 2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane (CAS 718641-97-5), a certified reference material (molecular formula C8H7BClFO2, MW 200.40 g/mol) for analytical method development and quality control.

The molecular framework of 2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane (C8H7BClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(3-Chloro-5-fluorophenyl)-1,3,2-dioxaborolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H7BClFO2
Molecular Weight200.40 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Cl-containing

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