2-Hydroxy-5-(trifluoromethylthio)phenylboronic acid CAS 2377609-27-1
| CAS No. | 2377609-27-1 |
| Molecular Formula | C7H6BF3O3S |
| Molecular Weight | 237.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Hydroxy-5-(trifluoromethylthio)phenylboronic acid (CAS 2377609-27-1), molecular formula C7H6BF3O3S and molecular weight 237.99 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Hydroxy-5-(trifluoromethylthio)phenylboronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.99 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6BF3O3S |
| Molecular Weight | 237.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
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