2-Bromo-4,5-difluoronitrobenzene CAS 321-17-5
| CAS No. | 321-17-5 |
| Molecular Formula | C6H2BrF2NO2 |
| Molecular Weight | 237.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Bromo-4,5-difluoronitrobenzene (CAS 321-17-5), a certified reference material (molecular formula C6H2BrF2NO2, MW 237.99 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Bromo-4,5-difluoronitrobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.99 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-Bromo-4,5-difluoronitrobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2BrF2NO2 |
| Molecular Weight | 237.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 1-Bromo-2,3-difluoro-4-nitrobenzene (CAS 1003708-24-4)
- 3-Bromo-2,4-difluoronitrobenzene, 97% (CAS 103977-78-2)
- 5-Bromo-1,2-difluoro-3-nitrobenzene (CAS 1261988-16-2)
- 1-Bromo-2,4-difluoro-3-nitrobenzene (CAS 1420800-30-1)
- 5-Bromo-1,3-difluoro-2-nitrobenzene (CAS 147808-42-2)
- 1-Bromo-2,5-difluoro-4-nitrobenzene, 97% (CAS 167415-27-2)
- 2-Bromo-1,4-difluoro-3-nitrobenzene (CAS 1804402-94-5)
- 1-Bromo-2,3-difluoro-5-nitrobenzene (CAS 374633-24-6)
Recommended Standards
- 2-Bromo-3,5-difluoroisonicotinic acid (CAS 2748453-60-1)
- 2-Bromo-4,6-difluoronitrobenzene (CAS 884494-38-6)
- 2-Bromo-3,4-Difluoronitrobenzene (CAS 350699-92-2)
- 2-Hydroxy-5-(trifluoromethylthio)phenylboronic acid (CAS 2377609-27-1)
- 4-(2-Bromo-4-ethylphenyl)thiosemicarbazide (CAS 1263377-22-5)
- 4-(4-Bromo-1,3-thiazol-2-yl)thiomorpholine (CAS 1502630-59-2)
- (E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)-phenyl)-3-(5-nitrothiophen-2-yl)acrylamide (CAS 1360614-48-7)
- 1-(2-Bromophenyl)-3-fluoropropan-1-one (CAS 1245806-55-6)
- (2E)-3-(3-CHloro-4-fluorophenyl)-2-propenoic acid, ethyl ester (CAS 695187-10-1)
- (S)-7-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-3,8-dicarboxylic acid (CAS 1445865-55-3)
- (1R,2R)-2-(4-Fluorophenyl)cyclopropanecarboxylic Acid (CAS 161711-27-9)
- 1-(tert-Butyl)-3-(6-((2-methoxybenzyl)oxy)pyrimidin-4-yl)urea (CAS 1396815-85-2)
- 2,2,2-Trifluoro-1-(5-methyl-1H-indol-3-yl)ethanol (CAS 160681-00-5)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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