6-Carboxy-2,3-difluorophenylboronic acid CAS 2377609-91-9
| CAS No. | 2377609-91-9 |
| Molecular Formula | C7H5BF2O4 |
| Molecular Weight | 201.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 201.92 g/mol gives 6-Carboxy-2,3-difluorophenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Carboxy-2,3-difluorophenylboronic acid (CAS 2377609-91-9) is a high-purity analytical reference standard with the molecular formula C7H5BF2O4 and a molecular weight of 201.92 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 6-Carboxy-2,3-difluorophenylboronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Carboxy-2,3-difluorophenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5BF2O4 |
| Molecular Weight | 201.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Carboxy Standards
- 4-Carboxy-2,5-difluorophenylboronic acid (CAS 1966890-13-0)
- 5-Carboxy-2,3-difluorophenylboronic acid (CAS 2377605-76-8)
- 3-Carboxy-2-chloropyridine-5-boronic acid (CAS 1451393-50-2)
- 4-Carboxy-2-methylquinoline 1-oxide (CAS 62542-43-2)
- 3-Carboxy-4-chlorophenylboronic Acid (CAS 913835-32-2)
- 4-Carboxy-2-chlorophenylboronic Acid (CAS 851335-09-6)
- 5-Carboxy-2-chlorophenylboronic Acid (CAS 913835-75-3)
- 4-Carboxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical (CAS 37149-18-1)
Recommended Standards
- 5-(Trifluoromethyl)benzo[c][1,2]oxaborol-1(3H)-ol (CAS 174671-50-2)
- 3-(Dihydroxyboranyl)-2,5-difluorobenzoic acid (CAS 2377605-94-0)
- Ferrous Bisglycinate (CAS 20150-34-9)
- 3,4-Difluoro-5-ethoxyphenylboronic acid (CAS 1162261-96-2)
- trans-Chalcone (CAS 614-47-1)
- Methyl (3-bromo-5-methylpyridin-2-yl)glycinate (CAS 1289097-37-5)
- 8-Methyl-2-(3-propoxyphenyl)quinoline-4-carboxylic acid (CAS 900705-40-0)
- Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)pent-4-enoate (CAS 143979-15-1)
- 3,5-Dihydro-4H-pyrimido[5,4-b]indol-4-one, 97% (CAS 61553-71-7)
- 7-Methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine (CAS 748807-62-7)
- 1-(2-(4-Methyl-6-morpholinopyridin-3-yl)pyrrolidin-1-yl)ethanone (CAS 1352525-79-1)
- 2-(3-Bromophenyl)-2-(methylamino)acetamide (CAS 1218221-61-4)
- 3-cyanobicyclo[1.1.1]pentane-1-carboxylic acid (CAS 83249-02-9)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
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