3-((tert-Butyldimethylsilyl)oxy)-2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine CAS 2377610-68-7
| CAS No. | 2377610-68-7 |
| Molecular Formula | C17H29BClNO3Si |
| Molecular Weight | 369.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-((tert-Butyldimethylsilyl)oxy)-2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-((tert-Butyldimethylsilyl)oxy)-2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2377610-68-7), molecular formula C17H29BClNO3Si and molecular weight 369.77 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((tert-Butyldimethylsilyl)oxy)-2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (C17H29BClNO3Si) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H29BClNO3Si |
| Molecular Weight | 369.77 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
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Recommended Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)-2-phenylacetamide (CAS 338406-89-6)
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- (3-chlorophenyl){4-[3-(trifluoromethyl)pyridin-2-yl]piperazino}methanone (CAS 260367-98-4)
- 3-(2-Chloro-6-fluorophenyl)-5-[(E)-2-[(3-methoxyphenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 338417-22-4)
- 1-(5-Bromothiophene-3-carbonyl)piperidine-3-carboxamide (CAS 1154000-10-8)
- 2-(Difluoromethyl)-4-iodo-3-methylpyridine-5-carboxaldehyde (CAS 1805548-70-2)
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