5-(2-((Tert-butyldimethylsilyl)oxy)ethyl)-5,7-dihydro-6H-benzo[d]pyrido[2,3-b]azepin-6-one CAS 1421438-86-9
| CAS No. | 1421438-86-9 |
| Molecular Formula | C21H28N2O2Si |
| Molecular Weight | 368.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-((Tert-butyldimethylsilyl)oxy)ethyl)-5,7-dihydro-6H-benzo[d]pyrido[2,3-b]azepin-6-one (CAS 1421438-86-9), molecular formula C21H28N2O2Si and molecular weight 368.54 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(2-((Tert-butyldimethylsilyl)oxy)ethyl)-5,7-dihydro-6H-benzo[d]pyrido[2,3-b]azepin-6-one (C21H28N2O2Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 368.54 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2-((Tert-butyldimethylsilyl)oxy)ethyl)-5,7-dihydro-6H-benzo[d]pyrido[2,3-b]azepin-6-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28N2O2Si |
| Molecular Weight | 368.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Tert Standards
- 1-(1-(3-((tert-Butyldimethylsilyl)oxy)-2-hydroxy-5-(trimethylsilyl)pent-4-yn-2-yl)cyclopropyl)ethan-1-one (CAS 1796927-82-6)
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Recommended Standards
- N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-(4-(thiophen-2-yl)piperidin-1-yl)acetamide (CAS 1396845-65-0)
- rel-2-((1R,2R)-2-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclopropyl)acetic acid (CAS 1498188-06-9)
- (R)-1-(1-Phenylethyl)-3-(3-(triethoxysilyl)propyl)urea (CAS 131206-15-0)
- rel-2-((1R,2S)-2-(((tert-Butyldiphenylsilyl)oxy)methyl)cyclopropyl)acetic acid (CAS 1498188-14-9)
- 2-Amino-4,7-dimethyl-1H-benzo[d]imidazol-5-ol (CAS 500138-30-7)
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- 6-fluoroquinazoline-2-carboxylic acid (CAS 1785337-73-6)
- 1-ethyl-1H-indol-5-amine (CAS 220844-49-5)
- (6,7-Dimethoxychroman-4-yl)methanamine (CAS 123891-64-5)
- 1-[(4-Hydroxyphenyl)methyl]cyclopropane-1-carboxylic acid (CAS 1512778-52-7)
- 2-(4-Benzyl-2-morpholinyl)ethanamine (CAS 112914-08-6)
- N-(4-chlorobenzyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-02-4)
- 3-(2-Oxobenzo[d]thiazol-3(2H)-yl)propanenitrile (CAS 881-13-0)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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