2-Chloroquinoline-8-boronic acid CAS 2377611-57-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2377611-57-7
Molecular FormulaC9H7BClNO2
Molecular Weight207.42 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloroquinoline-8-boronic acid CAS 2377611-57-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 207.42 g/mol gives 2-Chloroquinoline-8-boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Chloroquinoline-8-boronic acid (CAS 2377611-57-7) is a high-purity analytical reference standard with the molecular formula C9H7BClNO2 and a molecular weight of 207.42 g/mol.

The molecular framework of 2-Chloroquinoline-8-boronic acid (C9H7BClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloroquinoline-8-boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H7BClNO2
Molecular Weight207.42 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentCl-containing
Nitrogen Atoms1

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