{6-[(4-Methoxyphenyl)methoxy]-5-(trifluoromethyl)pyridin-3-yl}boronic acid CAS 2377611-90-8
| CAS No. | 2377611-90-8 |
| Molecular Formula | C14H13BF3NO4 |
| Molecular Weight | 327.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), {6-[(4-Methoxyphenyl)methoxy]-5-(trifluoromethyl)pyridin-3-yl}boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
{6-[(4-Methoxyphenyl)methoxy]-5-(trifluoromethyl)pyridin-3-yl}boronic acid (CAS 2377611-90-8) is a high-purity analytical reference standard with the molecular formula C14H13BF3NO4 and a molecular weight of 327.06 g/mol.
The molecular framework of {6-[(4-Methoxyphenyl)methoxy]-5-(trifluoromethyl)pyridin-3-yl}boronic acid (C14H13BF3NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13BF3NO4 |
| Molecular Weight | 327.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methoxyphenyl Standards
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- 3-(4-Methoxyphenyl)-2-[2-(4-methoxyphenyl)hydrazono]-3-oxopropanal oxime (CAS 339279-51-5)
- N-[(2-Methoxyphenyl)methyl]-2-methyl-3-oxo-2H,3H,4H-pyrido[3,2-b][1,4]oxazine-2-carboxamide (CAS 861211-37-2)
- 1-(4-Methoxyphenyl)-4-(4-nitrophenyl)-1H-imidazole-2-thiol (CAS 97814-14-7)
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Recommended Standards
- 2-Iodo-3-methyl-6-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine (CAS 2138063-20-2)
- 3-Bromo-5-(pentafluoro-λ6-sulfanyl)benzoic acid (CAS 1180675-98-2)
- N-[4-bromo-2-nitro-6-(trifluoromethyl)phenyl]acetamide (CAS 179062-00-1)
- 3-Bromo-2-hydroxy-5-(pentafluoro-lambda6-sulfanyl)benzaldehyde (CAS 1208718-46-0)
- (S)-1-Boc-3-Dimethylaminomethylpyrrolidine hydrochloride (CAS 1246643-15-1)
- (1S,2S,4S,5R)-2-(1H-Indol-2-yl)-5-vinylquinuclidine (CAS 61119-84-4)
- Amino(3-methylphenyl)acetic acid (CAS 187979-43-7)
- 2-((5-Bromopyridin-2-yl)oxy)-2-methylpropanoic acid (CAS 898265-49-1)
- n′-[[1-(hydroxymethyl)cyclopropyl]methyl]-n,n-dimethylsulfamide (CAS 1423517-50-3)
- (3,5-Difluorobenzyl)hydrazine hydrochloride (CAS 1864073-05-1)
- 5,5-Difluoro-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid (CAS 1780733-00-7)
- Glycine beta-Naphthylamide (CAS 716-94-9)
- N-alpha-Boc-L-tryptophan Methyl Ester (CAS 33900-28-6)
- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
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