(2,3,4,5,6-pentafluorophenyl) 3-(2,4-dioxohexahydropyrimidin-1-yl)-4-methoxy-benzoate CAS 2377643-63-3
| CAS No. | 2377643-63-3 |
| Molecular Formula | C18H11F5N2O5 |
| Molecular Weight | 430.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2,3,4,5,6-pentafluorophenyl) 3-(2,4-dioxohexahydropyrimidin-1-yl)-4-methoxy-benzoate (C18H11F5N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(2,3,4,5,6-pentafluorophenyl) 3-(2,4-dioxohexahydropyrimidin-1-yl)-4-methoxy-benzoate (CAS 2377643-63-3), molecular formula C18H11F5N2O5 and molecular weight 430.28 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11F5N2O5 |
| Molecular Weight | 430.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related pentafluorophenyl Standards
- Pentafluorophenyl 1-(thieno[3,2-d]pyrimidin-4-yl)piperidine-4-carboxylate (CAS 916766-92-2)
- Pentafluorophenyl 4-amino-3-iodobenzoate (CAS 1086375-59-8)
- (2,3,4,5,6-pentafluorophenyl) 4-chloro-3-(2,4-dioxohexahydropyrimidin-1-yl)benzoate (CAS 2633633-39-1)
- Pentafluorophenyl 5-bromo-4-methyl-1,3-thiazole-2-sulfonate (CAS 1421605-11-9)
- Pentafluorophenyl 2-(morpholin-4-ylsulphonyl)benzoate (CAS 950603-27-7)
- 2,3,4,5,6-Pentafluorophenyl 4-bromo-2-chlorobenzenesulfonate (CAS 886361-22-4)
- Bis(pentafluorophenyl) oxalate (CAS 16536-48-4)
- Bis(pentafluorophenyl)phenylphosphine (CAS 5074-71-5)
Recommended Standards
- 2-(Phenylcarbamoyl)phenyl 2-(2,4-Dichlorophenoxy)propanoate (CAS 1385694-59-6)
- 2-(4-(Benzyloxy)-2-chlorobenzoyl)-N-(4-chlorophenyl)hydrazine-1-carboxamide (CAS 478040-00-5)
- 2-(4-Bromophenyl)-N-(2-(3-(4-fluorophenyl)-6-oxopyridazin-1(6H)-yl)ethyl)acetamide (CAS 921851-24-3)
- 4-(Benzyloxy)-2-chloro-N-{[(3-chlorophenyl)carbamoyl]amino}benzamide (CAS 478039-99-5)
- ethyl 4-cyclopropyl-1H-pyrrole-3-carboxylate (CAS 936720-85-3)
- 2-Amino-5-[(3-fluorophenyl)methyl]-5-phenyl-4,5-dihydro-1H-imidazol-4-one (CAS 1354939-37-9)
- 3-(6-Methylpyridin-2-yl)isoquinolin-1-amine (CAS 66009-87-8)
- 3-((Carboxymethyl)amino)pyrrolidine-1-carboxylic acid (CAS 478272-62-7)
- 4-Bromo-1-methyl-3-propyl-1H-pyrazole-5-carboxylic acid (CAS 128537-50-8)
- Methyl (S)-2-(1-((benzyloxy)carbonyl)pyrrolidin-2-yl)-5-methyloxazole-4-carboxylate (CAS 182866-76-8)
- 2-Bromo-4-(4-(dimethylamino)-piperidin-1-yl)nitrobenzene (CAS 1779127-73-9)
- Lusutrombopag Impurity 51 (CAS CATO-C4X-208451)
- 4-Amino-2-methylbenzoxazole (CAS 342897-54-5)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
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