Lusutrombopag Impurity 51 CAS CATO-C4X-208451
| CAS No. | CATO-C4X-208451 |
| Molecular Formula | C17H19Cl2NO4 |
| Molecular Weight | 372.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lusutrombopag Impurity 51 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Lusutrombopag Impurity 51 (CAS CATO-C4X-208451, C17H19Cl2NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lusutrombopag Impurity 51 (C17H19Cl2NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H19Cl2NO4 |
| Molecular Weight | 372.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lusutrombopag Standards
- Lusutrombopag Impurity 25 (CAS CATO-C4X-208425)
- Lusutrombopag Impurity 52 (CAS CATO-C4X-208452)
- Lusutrombopag Impurity 50 (CAS CATO-C4X-208450)
- Lusutrombopag Impurity 45 (CAS CATO-C4X-208445)
- Lusutrombopag Impurity 86 (CAS CATO-C4X-208486)
- Lusutrombopag Impurity N4 (CAS 1110767-98-0)
- Lusutrombopag Impurity 9 (CAS CATO-C4X-20849)
- Lusutrombopag Impurity 23 (CAS CATO-C4X-208423)
Recommended Standards
- Carboplatin Impurity 10 (CAS 873662-13-6)
- Ethyl (R)-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate (CAS 1047975-40-5)
- tert-Butyl 3-(3-(3-iodopropoxy)propoxy)propanoate (CAS 2230826-08-9)
- (S)-Ethyl 3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate (CAS 1159502-91-6)
- Lomefloxacin Impurity 21 (CAS CATO-C4X-207321)
- Vinpocetine Impurity 2 (Oxime) (CAS 102341-40-2)
- Icatibant Impurity 5 Acetate (CAS CATO-C4X-23615)
- 2-Mercapto-3-butanol, mixture of isomers (CAS 37887-04-0)
- 3-Cyclopropoxypyridin-2-amine (CAS 1243459-41-7)
- Methyl 2-(7-Chloro-3-indolyl)-2-oxoacetate (CAS 203719-78-2)
- Myristylpicoline (CAS 108418-28-6)
- 2-Bromo-1,5-dimethyl-1H-benzo[d]imidazole (CAS 1541419-66-2)
- 4-(3-(4-Bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic acid (CAS 313399-13-2)
- Semaglutide impurity 277 (CAS CATO-C4X-2226277)
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