1-Chloro-2-(methoxymethyl)-3-(trifluoromethyl)benzene CAS 2379321-58-9
| CAS No. | 2379321-58-9 |
| Molecular Formula | C9H8ClF3O |
| Molecular Weight | 224.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Chloro-2-(methoxymethyl)-3-(trifluoromethyl)benzene (C9H8ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-Chloro-2-(methoxymethyl)-3-(trifluoromethyl)benzene (CAS 2379321-58-9) is a high-purity analytical reference standard with the molecular formula C9H8ClF3O and a molecular weight of 224.61 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClF3O |
| Molecular Weight | 224.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-N-ethyl-5-(trifluoromethyl)pyridin-2-amine (CAS 1042499-48-8)
- 2-chloro-1-[4-(trifluoromethyl)phenyl]ethan-1-ol (CAS 1070686-96-2)
- (1R)-2-chloro-1-[4-(trifluoromethyl)phenyl]ethan-1-ol (CAS 1072105-58-8)
- 6-Chloro-N,N-dimethyl-4-(trifluoromethyl)pyridin-2-amine (CAS 1160994-88-6)
- 2-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)ethan-1-amine (CAS 1165931-94-1)
- 2-(6-Chloro-4-(trifluoromethyl)pyridin-3-yl)ethan-1-amine (CAS 1256788-40-5)
- 4-Chloro-2-(propan-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 126439-51-8)
- 2-(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)ethan-1-amine (CAS 1360883-59-5)
Recommended Standards
- 1-[4-chloro-3-(trifluoromethyl)phenyl]ethan-1-ol (CAS 348-84-5)
- 1-Chloro-3-(methoxymethyl)-5-(trifluoromethyl)benzene (CAS 2364584-72-3)
- 1-[2-chloro-6-(trifluoromethyl)pyridin-3-yl]ethan-1-amine (CAS 944904-54-5)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethan-1-amine (CAS 658066-44-5)
- Picene-5,6-dione (CAS 24743-25-7)
- 5-Bromo-1,3,4-thiadiazole-2-carbonitrile (CAS 916889-37-7)
- (3R,4S)-rel-1-(tert-Butoxycarbonyl)-4-(2-fluorophenyl)pyrrolidine-3-carboxylic acid (CAS 1414580-85-0)
- H-D-Homoser-OH (CAS 6027-21-0)
- (S)-b-Amino-3-bromobenzenepropanol (CAS 468740-95-6)
- O-tert-Butylcabonyl HU 210 (CAS 113418-02-3)
- 5-Methoxynaphthalen-1-amine (CAS 6271-81-4)
- (Z)-11-hexadecenylacetate (CAS 34010-21-4)
- Octreotide Impurity 31 (CAS CATO-C4X-152031)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com