(2-Chloro-6-(trifluoromethyl)phenyl)(4-methylpiperazin-1-yl)methanone CAS 2379321-97-6

Purity 97%+In StockPharmaceutical Standards
CAS No.2379321-97-6
Molecular FormulaC13H14ClF3N2O
Molecular Weight306.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-Chloro-6-(trifluoromethyl)phenyl)(4-methylpiperazin-1-yl)methanone CAS 2379321-97-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 306.71 g/mol gives (2-Chloro-6-(trifluoromethyl)phenyl)(4-methylpiperazin-1-yl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies (2-Chloro-6-(trifluoromethyl)phenyl)(4-methylpiperazin-1-yl)methanone (CAS 2379321-97-6), a certified reference material (molecular formula C13H14ClF3N2O, MW 306.71 g/mol) for analytical method development and quality control.

The molecular framework of (2-Chloro-6-(trifluoromethyl)phenyl)(4-methylpiperazin-1-yl)methanone (C13H14ClF3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H14ClF3N2O
Molecular Weight306.71 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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