2-Fluoro-3-hydroxy-4-(trifluoromethyl)benzoic acid CAS 2379321-98-7

Purity 97%+In StockPharmaceutical Standards
CAS No.2379321-98-7
Molecular FormulaC8H4F4O3
Molecular Weight224.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-3-hydroxy-4-(trifluoromethyl)benzoic acid CAS 2379321-98-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 224.11 g/mol gives 2-Fluoro-3-hydroxy-4-(trifluoromethyl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Fluoro-3-hydroxy-4-(trifluoromethyl)benzoic acid (CAS 2379321-98-7), molecular formula C8H4F4O3 and molecular weight 224.11 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C8H4F4O3, 2-Fluoro-3-hydroxy-4-(trifluoromethyl)benzoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 224.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H4F4O3
Molecular Weight224.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF-containing

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