2-(5-Chlorobenzo[b]thiophen-3-yl)acetonitrile CAS 23799-60-2
| CAS No. | 23799-60-2 |
| Molecular Formula | C10H6ClNS |
| Molecular Weight | 207.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(5-Chlorobenzo[b]thiophen-3-yl)acetonitrile (C10H6ClNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(5-Chlorobenzo[b]thiophen-3-yl)acetonitrile (CAS 23799-60-2), molecular formula C10H6ClNS and molecular weight 207.68 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(5-Chlorobenzo[b]thiophen-3-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNS |
| Molecular Weight | 207.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorobenzo Standards
- 2-(5-Chlorobenzo[b]thiophen-2-yl)acetonitrile (CAS 23799-62-4)
- 2-(7-Chlorobenzo[d]thiazol-2-yl)acetonitrile (CAS 157764-09-5)
- 1-(6-Chlorobenzo[d]oxazol-2-yl)propan-2-one (CAS 83334-51-4)
- 2-Butyl-5-chlorobenzo[d]oxazole (CAS 866142-97-4)
- N-(6-Chlorobenzo[d]isoxazol-3-yl)acetamide (CAS 1195331-54-4)
- N-(5-Chlorobenzo[d]oxazol-2-yl)acetamide (CAS 13988-20-0)
- 1-(5-Chlorobenzo[d]oxazol-2-yl)guanidine (CAS 332144-07-7)
- 2-(5-Chlorobenzo[d]oxazol-2-yl)acetamide (CAS 35783-57-4)
Recommended Standards
- 3-Chloro-4-methylbenzo[b]thiophene-2-carbonitrile (CAS 337469-40-6)
- 1,2,5-Trimethyl-1H-pyrrole-3-sulfonyl chloride (CAS 499770-93-3)
- 4-Chloro-5-((isopropylthio)methyl)isoxazol-3(2H)-one (CAS 89660-94-6)
- 1-Cyanocyclohexane-1-sulfonyl chloride (CAS 1935075-12-9)
- 2,6-dimethylnicotinic acid (CAS 5860-71-9)
- 1,3-Dimethyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 67074-64-0)
- (E)-4-((4,4-dicyano-3-(dimethylamino)buta-1,3-dien-1-yl)amino)-N,N-dimethylbenzenesulfonamide (CAS 338773-75-4)
- Safrazine HCl (CAS 7296-30-2)
- N-(4,6-Di-tert-butyl-2-methyl-3-nitrophenyl)formamide (CAS 101270-19-3)
- Riociguat impurity 27 (CAS CATO-C4X-174927)
- 8-Methyl-5-nitroquinolin-6-amine (CAS 77094-07-6)
- Ethyl 4-bromo-6-chloropicolinate (CAS 1806059-73-3)
- 4-(Difluoromethoxy)-3-ethoxybenzoic acid (CAS 162401-63-0)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
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