8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine hydrobromide CAS 2379918-43-9
| CAS No. | 2379918-43-9 |
| Molecular Formula | C7H4ClF3N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine hydrobromide is closely related to a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine hydrobromide (CAS 2379918-43-9) is a high-purity analytical reference standard with the molecular formula C7H4ClF3N4HBr and a molecular weight of 317.49 g/mol.
8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine hydrobromide (C7H4ClF3N4HBr) contains a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3N4 HBr |
| Molecular Weight | 317.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 3-[(2-Chloro-4-methylsulfonyl)phenoxy]benzoic acid (CAS 1000018-31-4)
- 6-Chloro-2-[2-(3-[(6-chloro-1-ethylbenz[c,d,]indole-2[1H]-ylidene)ethylidene]-2-phenyl-1-cyclopenten-1-yl)ethenyl]-1-ethylbenz[c,d]indolium tetrafluoroborate (CAS 100012-45-1)
- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
- (3-Chloro-2-fluoro-5-iodophenyl)methanol (CAS 1000162-10-6)
- 3-Chloro-2-fluoro-5-nitrobenzoic acid (CAS 1000162-34-4)
- 2-Chloro-N-(piperidin-4-yl)-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-amine hydrochloride (CAS 1000207-51-1)
- 4-chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine (CAS 1000303-40-1)
Recommended Standards
- Cyclopentyl(cyclopropyl)methanone (CAS 58774-11-1)
- 1-Iodo-5-methylnaphthalene (CAS 1261623-29-3)
- 3-Chloro-5-(naphthalen-2-yl)phenol (CAS 1262000-94-1)
- Methyl 3-(((tert-butyldimethylsilyl)oxy)methyl)cyclobutane-1-carboxylate (CAS 1848239-63-3)
- N-(6-(Methylsulfonyl)benzo[d]thiazol-2-yl)isoxazole-5-carboxamide (CAS 941868-97-9)
- Nickel(II) hydroxide (CAS 12054-48-7)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one (CAS 1267046-10-5)
- 3-(6-Fluoropyridin-3-yl)-5-methylbenzaldehyde (CAS 1206969-42-7)
- 3-(2,2-dimethylpropyl)-1H-pyrazol-5-amine (CAS 377079-77-1)
- D-Gln24-Tirzepatide (CAS CATO-CPTD788910)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com