6-(Trifluoromethyl)-2H-spiro[benzo[b]thiophene-3,4'-piperidine] CAS 2379928-32-0
| CAS No. | 2379928-32-0 |
| Molecular Formula | C13H14F3NS |
| Molecular Weight | 273.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(Trifluoromethyl)-2H-spiro[benzo[b]thiophene-3,4'-piperidine] (C13H14F3NS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-(Trifluoromethyl)-2H-spiro[benzo[b]thiophene-3,4'-piperidine] (CAS 2379928-32-0) is a high-purity analytical reference standard with the molecular formula C13H14F3NS and a molecular weight of 273.32 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H14F3NS |
| Molecular Weight | 273.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 2-(4-(4-(Trifluoromethyl)phenyl)piperazin-1-yl)ethan-1-amine (CAS 681482-58-6)
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- {1-methyl-2-[4-(trifluoromethyl)phenyl]piperidin-3-yl}methanol (CAS 1315367-16-8)
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Recommended Standards
- 2-(2-(Dimethylamino)pyrimidin-4-yl)-1H-purine-6(7H)-thione (CAS 90185-54-9)
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- Flufenacet-methylsulfone (CAS 861391-80-2)
- (1R,3S)-1-(Boc-amino)-3-(Cbz-amino)cyclopentane (CAS 774212-79-2)
- MEGA-10 (CAS 85261-20-7)
- 5-Isothiocyanato-1,3-dimethyl-1H-pyrazole (CAS 205246-65-7)
- N-Boc-3-chloro-L-phenylalanine (CAS 114873-03-9)
- 2-Hydroxysuccinic acid, potassium salt (CAS 585-09-1)
- Bisindolylmaleimide II, 98% (CAS 137592-45-1)
- 4-(1-Cyano-1-methylethyl)-2-fluorophenylboronic acid (CAS 1793003-65-2)
- Verteporfin Impurity 7 (CAS CATO-C4X-35497)
- 1-(4-Fluorophenyl)-3-hydroxy-2-(methylsulfonyl)propan-1-one (CAS 1707374-34-2)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
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