6-Hydroxyindole CAS 2380-86-1

Purity >95%In StockPharmaceutical Standards
CAS No.2380-86-1
Molecular FormulaC8H7NO
Molecular Weight133.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Hydroxyindole CAS 2380-86-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 133.15 g/mol gives 6-Hydroxyindole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-Hydroxyindole (CAS 2380-86-1), molecular formula C8H7NO and molecular weight 133.15 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-Hydroxyindole (C8H7NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7NO
Molecular Weight133.15 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Nitrogen Atoms1

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