Phenylephrine 4,6-DMTQ Impurity(Peak-1) CAS 23824-24-0
| CAS No. | 23824-24-0 |
| Molecular Formula | C10H13NO2 |
| Molecular Weight | 179.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Phenylephrine 4,6-DMTQ Impurity(Peak-1) (CAS 23824-24-0, C10H13NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Phenylephrine 4,6-DMTQ Impurity(Peak-1) (C10H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Phenylephrine 4,6-DMTQ Impurity(Peak-1) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13NO2 |
| Molecular Weight | 179.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Phenylephrine Standards
- Phenylephrine Impurity 100 (CAS 1026633-55-5)
- Phenylephrine 4,6-DMTQ Impurity(Peak-2) (CAS 23824-25-1)
- Phenylephrine Impurity 35 (CAS 57236-57-4)
- Phenylephrine Impurity N21 (CAS 2292095-11-3)
- Phenylephrine Impurity 46 (CAS 54-06-8)
- Phenylephrine Impurity 36 (CAS CATO-C4X-146736)
- Phenylephrine Impurity 56 (CAS CATO-C4X-146756)
- Phenylephrine Impurity 48 (CAS 925430-39-3)
Recommended Standards
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- Alogliptin Impurity 62 (CAS 607376-86-3)
- (4-(Octyloxy)phenyl)(phenyl)iodonium (CAS 121239-74-5)
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- 1-(4-Chloro-2-fluorophenyl)pyrrolidin-2-one (CAS 190276-04-1)
- 5-Iodo-1-methylindolin-2-one (CAS 1332583-82-0)
- Nitro Ropinirole(USP Open Ring) (CAS 720656-64-4)
- 3-Cyclopropoxy-5-(dimethylamino)benzoic acid (CAS 1243456-96-3)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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