Tofacitinib Impurity 207 CAS 2382711-65-9
| CAS No. | 2382711-65-9 |
| Molecular Formula | C32H40N12O2 |
| Molecular Weight | 624.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tofacitinib Impurity 207 (C32H40N12O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tofacitinib Impurity 207 (CAS 2382711-65-9) is a certified pharmaceutical impurity reference standard with the molecular formula C32H40N12O2 and a molecular weight of 624.74 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tofacitinib Impurity 207 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H40N12O2 |
| Molecular Weight | 624.74 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 12 |
Related Tofacitinib Standards
- Tofacitinib Impurity 156 (CAS 2102040-00-4)
- Tofacitinib Impurity 81 (CAS 2315287-12-6)
- Tofacitinib Impurity 115 (CAS CATO-C4X-1079115)
- Tofacitinib Impurity 101 (CAS CATO-C4X-1079101)
- Tofacitinib Impurity 174 (CAS CATO-C4X-1079174)
- Tofacitinib Impurity 97 (CAS CATO-C4X-107997)
- Tofacitinib Impurity 18 (CAS 2504210-41-5)
- Tofacitinib Impurity 49 (CAS 2459302-78-2)
Recommended Standards
- Manidipine impurity 5 (CAS 89226-51-7)
- JKC-301 (CAS 136553-96-3)
- Landiolol Impurity 78 (CAS CATO-C4X-262178)
- Fmoc-D-Gln(Mtt)-OH (CAS 200638-37-5)
- Roxatidine Impurity 28 (CAS CATO-C4X-121328)
- Sparfloxacin Impurity 3 Sodium Salt (CAS 1348790-48-6 (free acid))
- Trazodone impurity 61 (CAS 80714-38-1)
- Spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 1,2-dihydro-1-methyl-2-oxo-, 1,1-dimethylethyl ester (CAS 497937-62-9)
- (3-Methylbenzyl)phosphonic acid (CAS 18945-65-8)
- Potassium cyclopentoxymethyltrifluoroborate (CAS 1027642-31-4)
- 1-(2,4-Difluorophenyl)-2-(propylthio)ethan-1-one (CAS 333744-26-6)
- Benzyl 2-((2-chloro-N-cyclopropylacetamido)methyl)piperidine-1-carboxylate (CAS 1353987-26-4)
- 1H-Pyrrolo[2,3-b]pyridine-3-carbonyl chloride (CAS 721882-63-9)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com