Tofacitinib Impurity 101 CAS CATO-C4X-1079101
| CAS No. | CATO-C4X-1079101 |
| Molecular Formula | C33H34N8O4S2 |
| Molecular Weight | 670.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tofacitinib Impurity 101 (CAS CATO-C4X-1079101, C33H34N8O4S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C33H34N8O4S2, Tofacitinib Impurity 101 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 670.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tofacitinib Impurity 101 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C33H34N8O4S2 |
| Molecular Weight | 670.80 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 2 |
Related Tofacitinib Standards
- Tofacitinib Impurity 156 (CAS 2102040-00-4)
- Tofacitinib Impurity 207 (CAS 2382711-65-9)
- Tofacitinib Impurity 81 (CAS 2315287-12-6)
- Tofacitinib Impurity 115 (CAS CATO-C4X-1079115)
- Tofacitinib Impurity 174 (CAS CATO-C4X-1079174)
- Tofacitinib Impurity 97 (CAS CATO-C4X-107997)
- Tofacitinib Impurity 18 (CAS 2504210-41-5)
- Tofacitinib Impurity 49 (CAS 2459302-78-2)
Recommended Standards
- Olmesartan N2-Trityl Anhydro Acid (CAS 1797891-24-7)
- Olmesartan Impurity 47 (CAS 1048948-15-7)
- Boc-NH-PEG11-CH2CH2N3 (CAS 2395004-21-2)
- Olmesartan impurity 100 (CAS 761404-82-4)
- Buspirone Impurity 03 (CAS 42940-56-7)
- Alvimopan Impurity 22 (CAS CATO-C4X-114522)
- Nicorandil impurity 60 (CAS CATO-C4X-190760)
- (2S,4R)-METHYL 4-((TERT-BUTOXYCARBONYL)AMINO)PYRROLIDINE-2-CARBOXYLATE HCL (CAS 1253792-94-7)
- oxalic acid tert-butyl N-(1-amino-3-phenylpropan-2-yl)-N-methylcarbamate (CAS 1820666-12-3)
- 4-Cyclopropoxy-6-methoxypicolinic acid (CAS 1243320-74-2)
- 4-Bromo-6-methoxypyrimidin-2-ol (CAS 1823870-48-9)
- 7-Hydrazinyl-3-methyl-4H-pyrimido[1,2-b]pyridazin-4-one (CAS 86674-01-3)
- 5,5'-(Propane-2,2-diyl)bis(2-(2-(furan-2-yl)propan-2-yl)furan) (CAS 61093-48-9)
- Peptide Impurity (CAS CATO-CPTD788810)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com