Salbutamol Impurity 21 CAS 2387728-91-6
| CAS No. | 2387728-91-6 |
| Molecular Formula | C15H25NO3 |
| Molecular Weight | 267.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Salbutamol Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Salbutamol Impurity 21 (CAS 2387728-91-6), a pharmacopoeial impurity reference standard (molecular formula C15H25NO3, MW 267.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Salbutamol Impurity 21 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H25NO3 |
| Molecular Weight | 267.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 202 (CAS CATO-C4X-1176202)
- Salbutamol Impurity 63 (CAS CATO-C4X-117663)
- Salbutamol Impurity 9 (CAS 754926-25-5)
- Salbutamol Impurity 104 (CAS 27566-09-2)
- Salbutamol impurity 166 (CAS 2919946-71-5)
- Salbutamol impurity 91 (CAS CATO-C4X-1176191)
- Salbutamol Impurity 81 (CAS CATO-C4X-1176181)
- Salbutamol Impurity 156 (CAS CATO-C4X-1176156)
Recommended Standards
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- 2-(Hydroxymethyl)-4-vinylphenol (CAS 96438-41-4)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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