Salbutamol Impurity 156 CAS CATO-C4X-1176156

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1176156
Molecular FormulaC9H8BrClO2
Molecular Weight263.52 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Salbutamol Impurity 156 CAS CATO-C4X-1176156 chemical structure

Description

CATO manufactures Salbutamol Impurity 156 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Salbutamol Impurity 156 (CAS CATO-C4X-1176156) is a certified pharmaceutical impurity reference standard with the molecular formula C9H8BrClO2 and a molecular weight of 263.52 g/mol.

The molecular framework of Salbutamol Impurity 156 (C9H8BrClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC9H8BrClO2
Molecular Weight263.52 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl/Br-containing

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