6,8-Dichloroquinolin-2(1H)-one CAS 23981-28-4
| CAS No. | 23981-28-4 |
| Molecular Formula | C9H5Cl2NO |
| Molecular Weight | 214.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6,8-Dichloroquinolin-2(1H)-one.
6,8-Dichloroquinolin-2(1H)-one (CAS 23981-28-4), molecular formula C9H5Cl2NO and molecular weight 214.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 6,8-Dichloroquinolin-2(1H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6,8-Dichloroquinolin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5Cl2NO |
| Molecular Weight | 214.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloroquinolin Standards
- 6,7-Dichloroquinolin-2(1H)-one (CAS 136472-34-9)
- 7,8-dichloroquinolin-3-ol (CAS 1492660-10-2)
- 3,7-Dichloroquinolin-4-ol (CAS 152210-26-9)
- 4,7-Dichloroquinolin-2(1H)-one (CAS 156820-88-1)
- 5,7-Dichloroquinolin-4-ol (CAS 171850-29-6)
- 2,3-Dichloroquinolin-8-ol (CAS 37396-44-4)
- 2,5-Dichloroquinolin-8-ol (CAS 56550-18-6)
- 3,5-Dichloroquinolin-4-ol (CAS 860502-05-2)
Recommended Standards
- 6,8-Dichloroquinazolin-4-amine (CAS 19808-38-9)
- 6,8-Dichloroquinolin-3-ol (CAS 860232-88-8)
- 6,7-Dichloroquinoxalin-2-amine (CAS 76002-68-1)
- 6,8-Dichloroquinolin-4-ol (CAS 57935-38-3)
- Bromisoval Impurity 2 (CAS 2274-08-0)
- N-(3,5-dimethoxybenzyl)-2-phenylethan-1-amine (CAS 345221-52-5)
- Methyl 3-{[(pyridin-3-ylmethyl)amino]-sulfonyl}thiophene-2-carboxylate (CAS 321715-39-3)
- Tropic acid (CAS 529-64-6)
- 2-tert-Butyl-5-methyl-1,3-dioxane-5-carboxylic Acid Vinyl Ester-d3 (CAS 1189464-68-3)
- copper sulfide (CAS 1317-40-4)
- 1-(5-Oxo-1-(p-tolyl)pyrrolidine-3-carbonyl)piperidine-4-carboxylic acid (CAS 1010929-78-8)
- (R)-(4-Benzyl-7-methyl-1,4-diazepan-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone (CAS 1620097-07-5)
- Fmoc-Lys(dansyl)-OH (CAS 118584-90-0)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com