Naproxen EP Impurity I CAS 23981-47-7
| CAS No. | 23981-47-7 |
| Molecular Formula | C13H12O3 |
| Molecular Weight | 216.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Naproxen EP Impurity I (CAS 23981-47-7) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12O3 and a molecular weight of 216.23 g/mol.
Based on its molecular formula C13H12O3, Naproxen EP Impurity I contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 216.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Naproxen EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H12O3 |
| Molecular Weight | 216.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Naproxen Standards
- Naproxen Acid (CAS 123050-98-6)
- Naproxen Impurity 2 (CAS 60756-73-2)
- Naproxen EP Impurity A (CAS 52079-10-4)
- Naproxen Impurity N1 (CAS 27602-75-1)
- Naproxen Impurity 6 (CAS 174172-95-3)
- Naproxen Dehydro Impurity (CAS 27602-79-5)
- Naproxen Impurity 41 (CAS CATO-C4X-170841)
- Naproxen Impurity 42 (CAS CATO-C4X-170842)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com