H-Glu-pNA CAS 24032-35-7
| CAS No. | 24032-35-7 |
| Molecular Formula | C11H13N3O5 |
| Molecular Weight | 267.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
H-Glu-pNA (CAS 24032-35-7), molecular formula C11H13N3O5 and molecular weight 267.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of H-Glu-pNA (C11H13N3O5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H13N3O5 |
| Molecular Weight | 267.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 3 |
Recommended Standards
- H-Glu(pNA)-OH (CAS 7300-59-6)
- 4,5,6,7-Tetrahydro-1-phenyl-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 1000933-91-4)
- H-D-Glu(pNA)-OH (CAS 60133-17-7)
- ethyl 2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylate (CAS 1005475-46-6)
- Potassium 2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate (CAS 24598-73-0)
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- 2-Bromo-7-methyl-3,4-dihydronaphthalen-1(2H)-one (CAS 104115-64-2)
- 3-Bromo-2-chloro-5,6-dimethylpyridine (CAS 1780882-71-4)
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