Ethyl 8-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate CAS 2407339-58-4
| CAS No. | 2407339-58-4 |
| Molecular Formula | C12H8F3N3O2 |
| Molecular Weight | 283.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 8-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Ethyl 8-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 2407339-58-4), a certified reference material (molecular formula C12H8F3N3O2, MW 283.21 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 8-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (C12H8F3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8F3N3O2 |
| Molecular Weight | 283.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Ethyl 7-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1555847-50-1)
- Ethyl 6-cyano-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 2407339-54-0)
- 2-Cyano-5-(3,5-dicarboxyphenyl)phenol (CAS 1261954-11-3)
- 2-Cyano-3-(5-(2-nitrophenyl)furan-2-yl)acrylamide (CAS 302552-93-8)
- (2E)-2-Cyano-N-(2-fluoro-4-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-enamide (CAS 338393-99-0)
- 2-Cyano-3-(5-(2-ethoxyphenyl)furan-2-yl)acrylic acid (CAS 853347-55-4)
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- N-(4-((3-cyano-4-methoxypyridin-2-yl)oxy)phenyl)acetamide (CAS 339016-72-7)
Recommended Standards
- N-(2,5-bis(trifluoromethyl)benzyl)cyclopropanamine (CAS 921630-38-8)
- 3-[3-(Trifluoromethyl)phenoxy]pyrazine-2-carboxamide (CAS 874832-16-3)
- n-[(2-bromophenyl)methyl]-1-methylpiperidin-4-amine (CAS 415953-59-2)
- 3-(Pyridin-3-yloxy)-5-(trifluoromethyl)picolinamide (CAS 338759-23-2)
- (2-(Diphenylphosphino)phenyl)methanol (CAS 81073-06-5)
- 4-(1,3-Dioxoisoindolin-2-yl)butyl 2-(methylthio)nicotinate (CAS 744240-29-7)
- 4-Bromo-2,3-dihydrobenzofuro[7,6-d]isoxazol-8-amine (CAS 2901798-01-2)
- 4-Bromo-2-morpholinobenzaldehyde (CAS 736990-80-0)
- 3-Cyano-6-methyl-4-(trifluoromethyl)picolinic acid (CAS 1565827-83-9)
- n-(Tert-butyl)-4-cyclopropylbutan-1-amine (CAS 1477834-71-1)
- 4-(Cyclopropanesulfonamidomethyl)benzoic acid (CAS 956325-61-4)
- (4-chloro-2-fluorophenyl)(3-methylthiophen-2-yl)methanone (CAS 1249924-08-0)
- Alogliptin Impurity 56 (CAS 454713-13-4)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
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