(E)-Ethyl 3-(4-chloro-2-(trifluoromethyl)phenyl)acrylate CAS 2413446-67-8
| CAS No. | 2413446-67-8 |
| Molecular Formula | C12H10ClF3O2 |
| Molecular Weight | 278.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-Ethyl 3-(4-chloro-2-(trifluoromethyl)phenyl)acrylate (CAS 2413446-67-8), molecular formula C12H10ClF3O2 and molecular weight 278.65 g/mol, is a CATO reference standard with documented purity and traceability.
(E)-Ethyl 3-(4-chloro-2-(trifluoromethyl)phenyl)acrylate (C12H10ClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-Ethyl 3-(4-chloro-2-(trifluoromethyl)phenyl)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClF3O2 |
| Molecular Weight | 278.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
Recommended Standards
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclobutanecarboxylic Acid (CAS 1314710-70-7)
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- 3-(6-Chloro-2H-chromen-3-yl)-1,2,4-oxadiazole-5-carboxylic acid (CAS 1269532-45-7)
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