5-(4-Chlorophenyl)pyrazine-2,3-dicarboxylic acid CAS 80356-77-0
| CAS No. | 80356-77-0 |
| Molecular Formula | C12H7ClN2O4 |
| Molecular Weight | 278.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorophenyl)pyrazine-2,3-dicarboxylic acid (CAS 80356-77-0) is a high-purity analytical reference standard with the molecular formula C12H7ClN2O4 and a molecular weight of 278.65 g/mol.
Based on its molecular formula C12H7ClN2O4, 5-(4-Chlorophenyl)pyrazine-2,3-dicarboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 278.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(4-Chlorophenyl)pyrazine-2,3-dicarboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7ClN2O4 |
| Molecular Weight | 278.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-(4-Chlorophenyl)-3-(2,6-difluorophenyl)prop-2-en-1-one (CAS 1095396-00-1)
- 2-(4-Chlorophenyl)-3-(difluoromethyl)benzofuran (CAS 821769-99-7)
- Ethyl 1-(4-chlorophenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1156510-03-0)
- Ethyl 1-(3-chlorophenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1159691-57-2)
- Ethyl 1-(2-chlorophenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1159691-65-2)
- (Z)-3-((2-(2-Chlorophenyl)hydrazineyl)methylene)-6-methyl-2H-pyran-2,4(3H)-dione (CAS 1164458-61-0)
- 3-[3-(3-Chlorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl]propanoic acid (CAS 1255784-12-3)
- 1-(2-Chlorophenyl)-3-(2-methoxypyrimidin-5-yl)urea (CAS 1396714-64-9)
Recommended Standards
- 3-Chloro-1-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-hydroxypyridazin-4(1H)-one (CAS 87008-90-0)
- 5-Chlorouridine (CAS 2880-89-9)
- (E)-Ethyl 3-(4-chloro-2-(trifluoromethyl)phenyl)acrylate (CAS 2413446-67-8)
- Eszopiclone Impurity 7 (CAS 43200-83-5)
- 2-(2-Fluorophenyl)cyclopentan-1-ol (CAS 1250622-40-2)
- benzyl(3-chloropropyl)methylamine (CAS 3161-52-2)
- (R)-Xyl-SDP (CAS 917377-75-4)
- 3,4-Difluoro-2-methoxybenzoic acid (CAS 875664-52-1)
- Methyl 2-(4-bromo-2-methylphenyl)acetate (CAS 958646-47-4)
- 3-Heptyl-7-methoxy-2-methylquinolin-4(1H)-one (CAS 354155-51-4)
- Tetrazole (CAS 27988-97-2)
- 2-Bromo-1-{imidazo[1,2-a]pyridin-3-yl}ethan-1-one (CAS 113559-18-5)
- (2-Bromo-5-fluorobenzyl)(3-chloro-5-fluorophenyl)sulfane (CAS 1443347-27-0)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com