Isoconazole EP Impurity A ( Miconazole EP Impurity A ) CAS 24155-42-8
| CAS No. | 24155-42-8 |
| Molecular Formula | C11H10Cl2N2O |
| Molecular Weight | 257.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Isoconazole EP Impurity A ( Miconazole EP Impurity A ) (C11H10Cl2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Isoconazole EP Impurity A ( Miconazole EP Impurity A ) (CAS 24155-42-8, C11H10Cl2N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Isoconazole EP Impurity A ( Miconazole EP Impurity A ) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2N2O |
| Molecular Weight | 257.12 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Isoconazole Standards
Recommended Standards
- 2-(4-(Bromomethyl)phenyl)-2-methylpropanoic acid (CAS 1072443-75-4)
- Ethyl 3-(2-bromophenyl)propionate (CAS 135613-33-1)
- 5-Bromo-2-butoxybenzaldehyde 515148-88-6 C11H13BrO2 V6334 (CAS 515148-88-6)
- Loxoprofen Impurity 104 (CAS 56607-18-2)
- Suvorexant Impurity 3 (CAS 1383717-13-2)
- Risdiplam Impurity 2 (CAS CATO-C4X-30122)
- Ertugliflozin Impurity 60 (CAS CATO-C4X-301160)
- 4-Bromo-1-ethylpyrazole (CAS 71229-85-1)
- 5-Cyclopropoxy-4-nitropicolinic acid (CAS 1243454-67-2)
- 4-Amino-1-methyl-5-nitropyrimidin-2(1H)-one (CAS 69100-00-1)
- 1-(2-Methyl-6-(piperazin-1-yl)pyridin-3-yl)ethan-1-amine (CAS 1355225-42-1)
- Tert-butyl 3-(bromomethyl)-5-chloro-1H-indazole-1-carboxylate (CAS 944899-43-8)
- N-(3-Chlorophenyl)hydrazinecarbothioamide (CAS 42135-76-2)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
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