4-Chloro-3-fluoro-2-methyl-6-(trifluoromethyl)aniline CAS 2415751-74-3
| CAS No. | 2415751-74-3 |
| Molecular Formula | C8H6ClF4N |
| Molecular Weight | 227.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-fluoro-2-methyl-6-(trifluoromethyl)aniline.
4-Chloro-3-fluoro-2-methyl-6-(trifluoromethyl)aniline (CAS 2415751-74-3) is a high-purity analytical reference standard with the molecular formula C8H6ClF4N and a molecular weight of 227.59 g/mol.
Based on its molecular formula C8H6ClF4N, 4-Chloro-3-fluoro-2-methyl-6-(trifluoromethyl)aniline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 227.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-3-fluoro-2-methyl-6-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF4N |
| Molecular Weight | 227.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-fluoro-N-(2,2,2-trifluoroethyl)aniline (CAS 1038369-35-5)
- 5-Chloro-2-fluoro-N-(2,2,2-trifluoroethyl)aniline (CAS 1155044-05-5)
- (S)-1-(2-Chloro-4-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1212915-61-1)
- (R)-1-(2-Chloro-4-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1212954-42-1)
- (R)-1-(4-chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213070-78-0)
- (R)-1-(3-Chloro-5-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213398-51-6)
- (S)-1-(4-chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213569-46-0)
- (S)-1-(3-Chloro-5-fluorophenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213630-75-1)
Recommended Standards
- 4-Chloro-2-fluoro-3-methyl-6-(trifluoromethyl)aniline (CAS 914635-40-8)
- 5-Chloro-7,8-difluoroisoquinoline-4-carbaldehyde (CAS 2920713-04-6)
- 3-Chloro-2-fluoro-6-(trifluoromethyl)benzylamine (CAS 261763-08-0)
- 3-Chloro-6-methoxy-4-nitro-1H-indazole (CAS 1000341-15-0)
- 4-Chloro-3-(diethylsulfamoyl)benzoic acid (CAS 59210-68-3)
- [(4-Bromo-2-chlorophenyl)methyl](3-methoxypropyl)amine (CAS 1601992-70-4)
- Prothipendyl-d6 Hydrochloride (CAS 1346604-67-8)
- tert-Butyl (3-aminobicyclo[3.2.1]octan-8-yl)carbamate (CAS 1638760-95-8)
- 1,2-Dichloro-3-iodo-4,5,6-trifluorobenzene (CAS 1803823-57-5)
- Ethyl 3-benzyl[1,2,4]triazolo[4,3-a]pyridine-8-carboxylate (CAS 1353506-72-5)
- 4-(3-Ethyl-n,5-dimethylisoxazole-4-carboxamido)butanoic acid (CAS 1098379-75-9)
- 5-Acetyl-1-(morpholinomethyl)-3,3-diphenylindolin-2-one (CAS 81252-98-4)
- 2-[2-(2,3-Dihydro-2-oxo-4-thiazolyl)ethyl]-1H-isoindole-1,3(2H)-dione (CAS 1504793-34-3)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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