tert-Butyl (3R,4R)-3-amino-4-(fluoromethyl)pyrrolidine-1-carboxylate CAS 2416992-75-9
| CAS No. | 2416992-75-9 |
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | 218.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-Butyl (3R,4R)-3-amino-4-(fluoromethyl)pyrrolidine-1-carboxylate (CAS 2416992-75-9) is a high-purity analytical reference standard with the molecular formula C10H19FN2O2 and a molecular weight of 218.27 g/mol.
The molecular framework of tert-Butyl (3R,4R)-3-amino-4-(fluoromethyl)pyrrolidine-1-carboxylate (C10H19FN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures tert-Butyl (3R,4R)-3-amino-4-(fluoromethyl)pyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | 218.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (3R,4R)-3-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 2166198-59-8)
- Tert-butyl (3R,4S)-3-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 2165671-41-8)
- tert-Butyl (2R,4R)-2-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 2166276-83-9)
- tert-Butyl (3R,4S)-3-fluoro-4-(methylamino)pyrrolidine-1-carboxylate (CAS 2757314-84-2)
- 3-Benzylpiperazine-2,5-dione (CAS 5037-75-2)
- 2,6-Dichloro-N-(4-chlorophenyl)-5-fluoronicotinamide (CAS 680217-80-5)
- 2-(2,6-dichlorophenyl)propan-2-amine hydrochloride (CAS 1240528-65-7)
- 5,7-dimethylimidazo[1,2-a]pyrimidine-3-carbaldehyde (CAS 1354951-09-9)
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- Methyl (S)-3-amino-3-(4-iodophenyl)propanoate (CAS 1160958-21-3)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com