tert-Butyl (3R,4S)-3-fluoro-4-(methylamino)pyrrolidine-1-carboxylate CAS 2757314-84-2
| CAS No. | 2757314-84-2 |
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | 218.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies tert-Butyl (3R,4S)-3-fluoro-4-(methylamino)pyrrolidine-1-carboxylate (CAS 2757314-84-2), a certified reference material (molecular formula C10H19FN2O2, MW 218.27 g/mol) for analytical method development and quality control.
tert-Butyl (3R,4S)-3-fluoro-4-(methylamino)pyrrolidine-1-carboxylate (C10H19FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H19FN2O2 |
| Molecular Weight | 218.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (3R,4S)-3-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 2165671-41-8)
- tert-Butyl (3R,4S)-4-amino-3-fluoropiperidine-1-carboxylate (CAS 907544-17-6)
- tert-Butyl (3R,4R)-3-amino-4-(fluoromethyl)pyrrolidine-1-carboxylate (CAS 2416992-75-9)
- Tert-butyl (3S,4R)-3-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 2165391-47-7)
- 4-Methoxy-6,8-dimethylquinoline-2-carbaldehyde (CAS 802906-31-6)
- 2-Tert-Butylphenol (CAS 88-18-6)
- 1-isopropylpyrazole-3-sulfonamide (CAS 1696838-10-4)
- Loxoprofen impurity 89 (CAS CATO-C4X-148889)
- 3-Cyclopropoxy-2-isopropylbenzenesulfonamide (CAS 1243460-18-5)
- 3-(1H-Pyrrol-1-yl)indolin-2-one (CAS 16176-35-5)
- N-(4-Bromo-1-methyl-1H-pyrazol-3-yl)pivalamide (CAS 1021999-38-1)
- Methyl 2,5-dibromopyridine-3-acetate (CAS 1803785-75-2)
- Micronomicin Sulfate (CAS CATO-C4X-23861)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
Why CATO?
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