5-Amino-2-{4-[4-(5-amino-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)phenoxy]phenyl}-2,3-dihydro-1h-isoindole-1,3-dione CAS 24200-78-0
| CAS No. | 24200-78-0 |
| Molecular Formula | C28H18N4O5 |
| Molecular Weight | 490.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-2-{4-[4-(5-amino-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)phenoxy]phenyl}-2,3-dihydro-1h-isoindole-1,3-dione.
5-Amino-2-{4-[4-(5-amino-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)phenoxy]phenyl}-2,3-dihydro-1h-isoindole-1,3-dione (CAS 24200-78-0), molecular formula C28H18N4O5 and molecular weight 490.47 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Amino-2-{4-[4-(5-amino-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)phenoxy]phenyl}-2,3-dihydro-1h-isoindole-1,3-dione (C28H18N4O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Amino-2-{4-[4-(5-amino-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)phenoxy]phenyl}-2,3-dihydro-1h-isoindole-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H18N4O5 |
| Molecular Weight | 490.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 4 |
Related Amino Standards
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Recommended Standards
- [4-(1,3-Benzothiazol-2-ylsulfanyl)-3-nitrophenyl]methyl 3-(trifluoromethyl)benzoate (CAS 320424-22-4)
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- 6-Chloro-2,8-diiodo-9-(tetrahydro-2H-pyran-2-yl)-9H-purine (CAS 1262785-79-4)
- H-Gly-Arg-Asp-Gly-Ser-OH (CAS 99131-38-1)
- Bupropion USP Related Compound C (CAS 152943-33-4)
- 2-Isopropyl-5-methoxyphenol (CAS 71745-50-1)
- 2-amino-1,2,3,4-tetrahydronaphthalene-2-carbonitrile hydrochloride (CAS 162098-82-0)
- 4-Chlorofuro[2,3-b]pyridine (CAS 193624-86-1)
- (S)-tert-Butyl 2-amino-4-hydroxy-3,3-dimethylbutanoate (CAS 2165969-82-2)
- 5-Hydroxy-1H-indole-2-carboxylic Acid Ethyl Ester (CAS 24985-85-1)
- Methyl (2E)-4-Oxo-4-(thiophen-2-yl)but-2-enoate (CAS 71132-39-3)
- 4-Allyltetrahydro-2H-pyran (CAS 1227788-85-3)
- 5-((6-(4-(Aminomethyl)piperidin-1-yl)pyrimidin-4-yl)amino)pyrazine-2-carbonitrile (CAS 1137475-21-8)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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