3-Amino-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide CAS 627053-26-3
| CAS No. | 627053-26-3 |
| Molecular Formula | C23H21F3N4OS2 |
| Molecular Weight | 490.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Amino-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-Amino-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 627053-26-3), molecular formula C23H21F3N4OS2 and molecular weight 490.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (C23H21F3N4OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H21F3N4OS2 |
| Molecular Weight | 490.56 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Amino Standards
- Methyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(2-fluorophenyl)-4H-pyran-3-carboxylate (CAS 445384-79-2)
- Methyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(4-fluorophenyl)-4H-pyran-3-carboxylate (CAS 445384-74-7)
- Methyl 6-amino-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl}sulfanyl)methyl]-4-(3-fluorophenyl)-4H-pyran-3-carboxylate (CAS 445384-81-6)
- 5-Amino-2-{4-[4-(5-amino-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)phenoxy]phenyl}-2,3-dihydro-1h-isoindole-1,3-dione (CAS 24200-78-0)
- 2-(4-(2-Amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-methoxyphenoxy)-N-(3-nitrophenyl)acetamide (CAS 333778-09-9)
- 3-Amino-N-(2-chlorophenyl)-4-(4-chlorophenyl)-6-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 332385-54-3)
- 3-Amino-N-(3-chlorophenyl)-6-(4-chlorophenyl)-4-phenylthieno[2,3-b]pyridine-2-carboxamide (CAS 334503-98-9)
- 3-Amino-6-(3,4-dimethoxyphenyl)-N-(4-fluorophenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 487037-03-6)
Recommended Standards
- 1,3-Bis(1H-benzo[d][1,2,3]triazol-1-yl)-1,3-bis(benzyloxy)propane (CAS 303756-59-4)
- N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-((3-cyano-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)acetamide (CAS 626228-69-1)
- 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH (CAS 124168-73-6)
- Linagliptin impurity 163 (CAS CATO-C4X-1101163)
- (1E)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-{4-[(2,4-dichlorophenyl)methoxy]phenyl}methanimine (CAS 297149-81-6)
- N'-acetyl-4-bromobenzohydrazide (CAS 74038-71-4)
- 1-cyclopentyl-2-(4-ethoxyphenoxy)ethan-1-one (CAS 1909324-71-5)
- N-(2-Fluorophenyl)-2,5-dimethylfuran-3-carboxamide (CAS 923114-16-3)
- 8-Methoxyimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 1315363-90-6)
- 3,5-Dibromofolic Acid (CAS 2536-53-0)
- Bromacil (CAS 314-40-9)
- Fmoc-Trp(Boc)-OH (CAS 143824-78-6)
- N-Hydroxy-2-(thiophen-2-yl)acetimidamide (CAS 59174-12-8)
- Semaglutide impurity 72 (CAS CATO-C4X-222672)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com