5,5-Bis(hydroxymethyl)-2-phenyl-1,3-dioxane CAS 2425-41-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2425-41-4
Molecular FormulaC12H16O4
Molecular Weight224.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5,5-Bis(hydroxymethyl)-2-phenyl-1,3-dioxane CAS 2425-41-4 chemical structure

Description

The occurrence of 5,5-Bis(hydroxymethyl)-2-phenyl-1,3-dioxane is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5,5-Bis(hydroxymethyl)-2-phenyl-1,3-dioxane (CAS 2425-41-4) is a high-purity analytical reference standard with the molecular formula C12H16O4 and a molecular weight of 224.25 g/mol.

5,5-Bis(hydroxymethyl)-2-phenyl-1,3-dioxane (C12H16O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H16O4
Molecular Weight224.25 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

Related Bis Standards

Recommended Standards

Why CATO?