1-Chloro-3-(4-methoxyphenyl)propan-2-one CAS 24253-13-2
| CAS No. | 24253-13-2 |
| Molecular Formula | C10H11ClO2 |
| Molecular Weight | 198.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 198.65 g/mol gives 1-Chloro-3-(4-methoxyphenyl)propan-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Chloro-3-(4-methoxyphenyl)propan-2-one (CAS 24253-13-2) is a high-purity analytical reference standard with the molecular formula C10H11ClO2 and a molecular weight of 198.65 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 1-Chloro-3-(4-methoxyphenyl)propan-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Chloro-3-(4-methoxyphenyl)propan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO2 |
| Molecular Weight | 198.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 6-Chloro-4-(isopropylamino)nicotinaldehyde (CAS 1012880-02-2)
- 2-Chloro-6-(cyclopentyloxy)pyrazine (CAS 1016697-18-9)
- 3-Chloro-5-(methylsulfonyl)-1,2,4-thiadiazole (CAS 10191-91-0)
- 5-Chloro-6-methyl-3-(pyrrolidin-1-yl)-1,2,4-triazine (CAS 1023818-03-2)
- Methyl 2-(5-chloro-2-methylphenyl)acetate (CAS 1076191-96-2)
- Methyl (2-chloro-6-methylphenyl)acetate (CAS 1076192-08-9)
- 3-(4-Chloro-3-methylphenyl)propanoic acid (CAS 1086386-05-1)
- 2-Chloro-N-ethyl-N-methylnicotinamide (CAS 112006-59-4)
Recommended Standards
- 1-Chloro-3-(3-methoxyphenyl)propan-2-one (CAS 24253-16-5)
- 1-Chloro-4-(1,3-dioxolan-2-ylmethyl)benzene (CAS 4412-51-5)
- 1-Chloro-3-(2-methoxyphenyl)propan-2-one (CAS 38694-34-7)
- 1-Chloro-4-hydrazinyl-5,6,7,8-tetrahydrophthalazine (CAS 66597-78-2)
- N-(1-Chloro-4-methyl-5H-pyrido[4,3-b]indol-8-yl)benzamide (CAS 915778-07-3)
- 2-Chloro-1-(tetrahydro-2H-pyran-2-yl)ethan-1-one (CAS 141061-07-6)
- 5-Chloro-2-ethylbenzofuran (CAS 39178-59-1)
- tert-Butyl (azetidin-3-ylmethyl)carbamate oxalate (CAS 1187929-81-2)
- 1,1,1-Trimethoxypentane (CAS 1251907-36-4)
- 2-(4-Bromophenyl)-4-chloro-6-isopropylpyrimidine (CAS 1153298-25-9)
- rac N-Methyl Epinephrine (CAS 554-99-4)
- N-(3-(1-(3-Fluorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl)-1,2,4-thiadiazol-5-yl)furan-2-carboxamide (CAS 931723-35-2)
- Cefotaxime Impurity 44 (CAS 47288-83-5)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com