2-(6,8-Difluoro-3-hydroxyquinolin-2-yl)isoindoline-1,3-dione CAS 2435612-56-7
| CAS No. | 2435612-56-7 |
| Molecular Formula | C17H8F2N2O3 |
| Molecular Weight | 326.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(6,8-Difluoro-3-hydroxyquinolin-2-yl)isoindoline-1,3-dione (CAS 2435612-56-7), a certified reference material (molecular formula C17H8F2N2O3, MW 326.25 g/mol) for analytical method development and quality control.
2-(6,8-Difluoro-3-hydroxyquinolin-2-yl)isoindoline-1,3-dione (C17H8F2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H8F2N2O3 |
| Molecular Weight | 326.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- (S)-9,10-difluoro-3-methyl-8-nitro-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid (CAS 236743-93-4)
- 2-{4-[2-(2,6-Difluoro-phenyl)-4,5-dihydro-oxazol-4-yl]-phenyl}-oxazole (CAS 1231482-74-8)
- Ethyl 2,2-difluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate (CAS 1683545-35-8)
- Ethyl 2-(3,5-difluoro-4-iodophenyl)acetate (CAS 2385942-02-7)
- Ethyl 3,4-difluoro-2-iodophenylcarbamate (CAS 1268052-94-3)
- 2,6-Difluoro-N-(2-hydroxy-2-methyl-4-(methylthio)butyl)benzenesulfonamide (CAS 1396746-33-0)
- 1-(2,6-Difluoro-4-iodopyridin-3-yl)-2,2-dimethylpropan-1-ol (CAS 2863533-23-5)
- 1-(2,6-Difluoro-4-iodopyridin-3-yl)-3-methylbutan-1-ol (CAS 2863532-75-4)
Recommended Standards
- 1-(2,4-Diphenyl-1,3-selenazol-5-yl)ethanone (CAS 807631-74-9)
- N1,N3-bis(2,4-difluorophenyl)malonamide (CAS 339096-50-3)
- (S)-3-(3-Bromophenoxy)-N-methyl-3-(thiophen-2-yl)propan-1-amine (CAS 2260747-62-2)
- 4-({[(4-bromothiophen-2-yl)methyl](methyl)amino}methyl)-N-methylpyridin-2-amine (CAS 1271451-74-1)
- Ethyl (2E)-4,4,4-trifluoro-3-[(4-methylphenyl)formamido]but-2-enoate (CAS 400087-75-4)
- 4-((8-Hydroxy-6-sulfonaphthalen-2-yl)amino)benzoic acid (CAS 5855-84-5)
- 7-fluoro-5-oxa-2-azaspiro[3.4]octane;hydrochloride (CAS 2387596-84-9)
- 2-((6-Methylpyridazin-3-yl)thio)acetic acid (CAS 89693-96-9)
- 1-(5-Methoxy-2-(trifluoromethyl)pyridin-4-yl)ethan-1-one (CAS 1256819-69-8)
- (Chloro(methoxy)methyl)benzene (CAS 35364-99-9)
- (5-Ethyl-2-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225180-38-9)
- 2-Acetamido-3-phenylprop-2-enoic acid (CAS 55065-02-6)
- 3,3-dimethyl-1,4-dioxane-2-carboxylic acid (CAS 1707364-90-6)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com