Ethyl (2E)-4,4,4-trifluoro-3-[(4-methylphenyl)formamido]but-2-enoate CAS 400087-75-4
| CAS No. | 400087-75-4 |
| Molecular Formula | C14H14F3NO3 |
| Molecular Weight | 301.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl (2E)-4,4,4-trifluoro-3-[(4-methylphenyl)formamido]but-2-enoate (C14H14F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Ethyl (2E)-4,4,4-trifluoro-3-[(4-methylphenyl)formamido]but-2-enoate (CAS 400087-75-4), a certified reference material (molecular formula C14H14F3NO3, MW 301.26 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl (2E)-4,4,4-trifluoro-3-[(4-methylphenyl)formamido]but-2-enoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14F3NO3 |
| Molecular Weight | 301.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Benzyl 4-oxo-2-(trifluoromethyl)piperidine-1-carboxylate (CAS 911298-12-9)
- ethyl 2-[(ethoxycarbonyl)amino]-3,3,3-trifluoro-2-isopropoxypropanoate (CAS 256332-88-4)
- Azinphos-methyl oxon (CAS 961-22-8)
- N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-(Trifluoromethyl)Benzamide (CAS 77694-32-7)
- 2-(1-Iodoethyl)-1-tosylpyrrolidin-3-ol (CAS 90778-73-7)
- 3-Cyclohexylbutanoic acid (CAS 4361-38-0)
- (1H-Inden-1-yl)phosphonic acid (CAS 387361-84-4)
- Naproxen Impurity 47 (CAS 99705-42-7)
- 4-Methoxy Retinoic Acid Methyl Ester (CAS 163808-81-9)
- N-cyclopentyl-N-methylmethanesulfonamide (CAS 1125413-04-8)
- N-Cyclohexyl-3-nitrobenzamide (CAS 2702-32-1)
- 2,4-Bis(propan-2-yl)benzoic acid (CAS 108961-55-3)
- 1,5-dimethyl-1H-pyrazole-4-sulfonyl chloride (CAS 1005613-94-4)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com