5-Hydroxy-2-naphthoic acid CAS 2437-18-5
| CAS No. | 2437-18-5 |
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 188.18 g/mol gives 5-Hydroxy-2-naphthoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Hydroxy-2-naphthoic acid (CAS 2437-18-5), molecular formula C11H8O3 and molecular weight 188.18 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H8O3, 5-Hydroxy-2-naphthoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 188.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
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- 8-Hydroxy-2-methylnaphthalene-1,4-dione (CAS 14777-17-4)
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Recommended Standards
- 5-formyl-1H-indole-2-carboxamide (CAS 877998-68-0)
- 5-Methyl-6-nitroquinoline (CAS 65745-70-2)
- 5-Aminoquinoline-8-carboxylic acid (CAS 80690-06-8)
- 5-Methyl-7-nitroquinoline (CAS 342043-94-1)
- (Z)-4-((Ethylthio)methylene)-3-methylisoxazol-5(4H)-one (CAS 61861-36-7)
- tert-Butyl (1R,2R,4S)-rel-2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 1000870-15-4)
- (S)-3,3'-Di-9-phenanthrenyl-[1,1'-binaphthalene]-2,2'-diol (CAS 957111-25-0)
- Methyl 2,4-dioxo-1,2,3,4-tetrahydropyrido[3,2-d]pyrimidine-6-carboxylate (CAS 1956332-21-0)
- 5-Chloro-2-methylsulfanyl-1,3-benzothiazole (CAS 3507-41-3)
- 6'-(Diethylamino)-2'-((2,4-dimethylphenyl)amino)-3'-methyl-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one (CAS 36431-22-8)
- 4-(Benzo[d][1,3]dioxol-5-ylmethyl)-N-(tert-butyl)piperazine-1-carbothioamide (CAS 497060-83-0)
- Calcitriol Impurity 20 (CAS CATO-C4X-151020)
- (5-(Dimethylcarbamoyl)-2-fluorophenyl)boronic acid (CAS 874289-46-0)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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