Linagliptin Impurity 80 CAS 2446799-71-7
| CAS No. | 2446799-71-7 |
| Molecular Formula | C20H17BrN6O2 |
| Molecular Weight | 453.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Linagliptin Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Linagliptin Impurity 80 (CAS 2446799-71-7) is a certified pharmaceutical impurity reference standard with the molecular formula C20H17BrN6O2 and a molecular weight of 453.29 g/mol.
The molecular framework of Linagliptin Impurity 80 (C20H17BrN6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H17BrN6O2 |
| Molecular Weight | 453.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 6 |
Related Linagliptin Standards
- Linagliptin Impurity 48 (CAS 853029-57-9)
- Linagliptin Impurity 72 (CAS CATO-C4X-110172)
- Linagliptin impurity 162 (CAS CATO-C4X-1101162)
- Linagliptin impurity 161 (CAS CATO-C4X-1101161)
- Linagliptin impurity 164 (CAS CATO-C4X-1101164)
- Linagliptin impurity 117 (CAS CATO-C4X-1101117)
- Linagliptin Impurity 135 (CAS CATO-C4X-1101135)
- Linagliptin Impurity 2 (CAS 2518331-40-1)
Recommended Standards
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- Teduglutide Impurity 2 (CAS CATO-C4X-23642)
- Bortezomib Impurity 49 (CAS 948294-96-0)
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- 2-Methanesulfonamidopropanoic acid (CAS 879123-60-1)
- 3-Oxo-N-(pyrrolidin-1-yl)butanamide (CAS 202801-00-1)
- 2,2-difluoro-2-(1-propyl-1H-imidazol-2-yl)acetic acid hydrochloride (CAS 1795185-87-3)
- Amorolfine Impurity 49 (CAS CATO-C4X-154249)
- HA Peptide (CAS 92000-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com