Empagliflozin Impurity 3 CAS 2452301-09-4
| CAS No. | 2452301-09-4 |
| Molecular Formula | C25H29ClO8 |
| Molecular Weight | 492.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 492.95 g/mol gives Empagliflozin Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Empagliflozin Impurity 3 (CAS 2452301-09-4) is a certified pharmaceutical impurity reference standard with the molecular formula C25H29ClO8 and a molecular weight of 492.95 g/mol.
Structurally, Empagliflozin Impurity 3 (C25H29ClO8) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 492.95 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H29ClO8 |
| Molecular Weight | 492.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 219 (CAS CATO-C4X-1065219)
- Empagliflozin Impurity 220 (CAS CATO-C4X-1065220)
- Empagliflozin Impurity 24 (CAS CATO-C4X-106524)
- Empagliflozin Impurity 9 (CAS CATO-C4X-10659)
- Empagliflozin Impurity 89 (CAS CATO-C4X-106589)
- Empagliflozin impurity 275 (CAS CATO-C4X-1065275)
- Empagliflozin impurity 212 (CAS CATO-C4X-1065212)
- Empagliflozin Impurity 76 (CAS CATO-C4X-106576)
Recommended Standards
- Apixaban Impurity 150 (CAS CATO-C4X-1088150)
- Apixaban Impurity 151 (CAS CATO-C4X-1088151)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(2-(p-tolylthio)pyridin-3-yl)methanone (CAS 1022407-10-8)
- Apixaban Impurity 43 (CAS 2029205-62-5)
- Gadobutrol Impurity 149 (CAS CATO-C4X-2120149)
- Loxoprofen impurity 90 (CAS CATO-C4X-148890)
- Icaritin Impurity 4 (CAS CATO-C4X-27644)
- Methyl 4-(((4-bromo-5-(dimethylamino)furan-2-yl)methylene)amino)benzoate (CAS 469895-89-4)
- n-(2-Methylbut-3-yn-2-yl)methanesulfonamide (CAS 1279876-13-9)
- 6,7-Difluorobenzoxazole-2(3H)-thione (CAS 195737-21-4)
- 1-(Pyrimidin-5-yl)propan-1-one (CAS 852180-02-0)
- 2-(2-Bromophenyl)pyrrolidine Oxalate (2:1) (CAS 1177278-80-6)
- 4-(1-Hydroxypentyl)thiophen-3-boronic acid (CAS 2096334-17-5)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com