Apixaban Impurity 151 CAS CATO-C4X-1088151
| CAS No. | CATO-C4X-1088151 |
| Molecular Formula | C26H25ClN4O4 |
| Molecular Weight | 492.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 492.95 g/mol gives Apixaban Impurity 151 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Apixaban Impurity 151 (CAS CATO-C4X-1088151, C26H25ClN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Apixaban Impurity 151 (C26H25ClN4O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apixaban Impurity 151 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H25ClN4O4 |
| Molecular Weight | 492.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban Impurity 150 (CAS CATO-C4X-1088150)
- Apixaban Impurity 43 (CAS 2029205-62-5)
- Apixaban Impurity 173 (CAS CATO-C4X-1088173)
- Apixaban Impurity 75 (CAS CATO-C4X-108875)
- Apixaban Impurity 32 (CAS CATO-C4X-108832)
- Apixaban Impurity 22 (CAS 1449510-64-8)
- Apixaban Impurity 62 (CAS CATO-C4X-108862)
- Apixaban Impurity 153 (CAS CATO-C4X-1088153)
Recommended Standards
- Empagliflozin Impurity 9 (CAS CATO-C4X-10659)
- Dapagliflozin Impurity 131 (CAS CATO-C4X-1138131)
- Empagliflozin Impurity 3 (CAS 2452301-09-4)
- Dapagliflozin Impurity 72 (CAS CATO-C4X-113872)
- Moxifloxacin impurity 131 (CAS CATO-C4X-1074131)
- Vortioxetine Impurity 26 (CAS 2243045-82-9)
- Dotinurad Impurity 18 (CAS CATO-C4X-249418)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com