4-(Difluoromethyl)-1,2,5-oxadiazole-3-carboxylic acid CAS 2452465-16-4
| CAS No. | 2452465-16-4 |
| Molecular Formula | C4H2F2N2O3 |
| Molecular Weight | 164.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-(Difluoromethyl)-1,2,5-oxadiazole-3-carboxylic acid (C4H2F2N2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 164.07 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-(Difluoromethyl)-1,2,5-oxadiazole-3-carboxylic acid (CAS 2452465-16-4), a certified reference material (molecular formula C4H2F2N2O3, MW 164.07 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H2F2N2O3 |
| Molecular Weight | 164.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3-nitro-1H-1,2,4-triazole (CAS 2137653-18-8)
- 1-(Difluoromethyl)-3,5-difluorobenzene (CAS 1208077-70-6)
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Recommended Standards
- 3,3,4,4,4-Pentafluorobutanol-2 (CAS 374-40-3)
- Methyl 2,2,3,3,3-Pentafluoropropyl Ether (CAS 378-16-5)
- 3,3,4,4,4-Pentafluorobutan-1-ol (CAS 54949-74-5)
- 1-ethoxy-1,1,2,2,2-pentafluoroethane 22052-81-9 Ethyl pentafluoroethyl ether (CAS 22052-81-9)
- n-(But-3-yn-1-yl)-4-ethylcyclohexan-1-amine (CAS 1340131-09-0)
- (4-(Difluoromethyl)-5-methoxy-6-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1805549-50-1)
- Methyl 3-acetoxy-6-bromo-1H-indole-4-carboxylate (CAS 1227270-87-2)
- (Dimethylcarbamoyl)-D-proline (CAS 1046139-15-4)
- 4-(Difluoromethoxy)-5-methoxy-2-nitrobenzoic acid (CAS 923170-53-0)
- 2-(4-Chloro-5-fluoropyridin-3-yl)acetonitrile (CAS 1807259-45-5)
- 1,4-Dioxaspiro[5.5]undecan-9-one (CAS 362706-72-7)
- 2-(3-Bromo-2-nitrophenyl)acetic acid (CAS 400629-31-4)
- n1-(Cyclopropylmethyl)-n3,n3-dimethylpropane-1,3-diamine (CAS 1154342-16-1)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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