4,7-dichloro-8-fluoro-2-methyl-pyrido[4,3-d]pyrimidine CAS 2454397-79-4
| CAS No. | 2454397-79-4 |
| Molecular Formula | C8H14Cl2FN3 |
| Molecular Weight | 242.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,7-dichloro-8-fluoro-2-methyl-pyrido[4,3-d]pyrimidine (CAS 2454397-79-4), molecular formula C8H14Cl2FN3 and molecular weight 242.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, fluorine/chlorine substitution, 4,7-dichloro-8-fluoro-2-methyl-pyrido[4,3-d]pyrimidine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,7-dichloro-8-fluoro-2-methyl-pyrido[4,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H14Cl2FN3 |
| Molecular Weight | 242.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related dichloro Standards
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Recommended Standards
- 4,4,5,5-Tetramethyl-2-(p-tolylethynyl)-1,3,2-dioxaborolane (CAS 872356-93-9)
- 4-Bromo-2-(piperidin-1-yl)pyrimidine (CAS 317830-89-0)
- 4,4,5,5-Tetramethyl-2-(o-tolylethynyl)-1,3,2-dioxaborolane (CAS 872356-94-0)
- 5-Bromo-2-(piperidin-1-yl)pyrimidine (CAS 57356-64-6)
- 2-Propenoic acid, 2-methyl-, polymer with ethene and potassium 2-methyl-2-propenoate (CAS 67892-74-4)
- 1-(4-(Pentafluoro-lambda6-sulfanyl)phenyl)ethan-1-one (CAS 401892-83-9)
- Zolpidem Impurity 42 (CAS 381717-12-0)
- 4'-Bromo-4-nitro-[1,1'-biphenyl]-2-carboxylic acid (CAS 886361-93-9)
- 1-Methyl-4-(prop-2-yn-1-yl)benzene (CAS 30342-96-2)
- 4-(4-Methoxycarbonyl-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester (CAS 281235-00-5)
- 4-(2-Naphthyl)aniline (CAS 209848-36-2)
- (R)-(-)-3,5-Dinitro-N-(1-phenylethyl)benzamide (CAS 69632-32-2)
- 7-Nitro-2,3-dihydro-1,4-benzodioxine-6-sulfonyl chloride (CAS 5279-54-9)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
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