2-Chloro-5-iodo-3-methoxypyridin-4-amine CAS 2454491-04-2
| CAS No. | 2454491-04-2 |
| Molecular Formula | C6H6ClIN2O |
| Molecular Weight | 284.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Chloro-5-iodo-3-methoxypyridin-4-amine (CAS 2454491-04-2), molecular formula C6H6ClIN2O and molecular weight 284.48 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-5-iodo-3-methoxypyridin-4-amine (C6H6ClIN2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 284.48 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClIN2O |
| Molecular Weight | 284.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-5-iodo-6-methoxy-2-methylpyrimidine (CAS 111079-20-0)
- 5-Chloro-3-ethoxy-2-iodopyrazine (CAS 1935932-65-2)
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