Ethyl 4-amino-6-chloro-5-methoxynicotinate CAS 2454491-05-3
| CAS No. | 2454491-05-3 |
| Molecular Formula | C9H11ClN2O3 |
| Molecular Weight | 230.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 4-amino-6-chloro-5-methoxynicotinate (CAS 2454491-05-3) is a high-purity analytical reference standard with the molecular formula C9H11ClN2O3 and a molecular weight of 230.65 g/mol.
Ethyl 4-amino-6-chloro-5-methoxynicotinate (C9H11ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11ClN2O3 |
| Molecular Weight | 230.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
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- 1-(3-Phenyl-1,2,4-oxadiazol-5-yl)propan-2-one (CAS 80628-80-4)
- 5-tert-Butyl-1,3-oxazole (CAS 1823916-34-2)
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- 2-(Benzo[b]thiophen-2-yl)pyridin-3-ol (CAS 1261973-39-0)
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- (R)-4-Benzyl-1-(4-bromophenyl)-6-(hydroxymethyl)piperazin-2-one (CAS 797037-85-5)
- Ethyl 4-chloro-8-methoxyquinoline-3-carboxylate (CAS 27568-05-4)
- Peptide 442 (CAS CATO-CPTD788442)
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