Sacubitril Impurity 24 CAS 2459446-52-5
| CAS No. | 2459446-52-5 |
| Molecular Formula | C28H37NO5 |
| Molecular Weight | 467.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sacubitril Impurity 24.
Sacubitril Impurity 24 (CAS 2459446-52-5) is a certified pharmaceutical impurity reference standard with the molecular formula C28H37NO5 and a molecular weight of 467.60 g/mol.
Sacubitril Impurity 24 (C28H37NO5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sacubitril Impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H37NO5 |
| Molecular Weight | 467.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
Related Sacubitril Standards
- Sacubitril Impurity 22 (CAS 2459446-53-6)
- Sacubitril impurity 47 (CAS CATO-C4X-280947)
- Sacubitril Impurity 33 (CAS CATO-C4X-280933)
- Sacubitril Impurity 34 (CAS CATO-C4X-280934)
- Sacubitril Impurity 29 (CAS CATO-C4X-280929)
- Sacubitril Impurity 35 (CAS CATO-C4X-280935)
- Sacubitril Impurity 20 (CAS 2459446-51-4)
- Sacubitril Impurity 37 (CAS CATO-C4X-280937)
Recommended Standards
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- Nemonoxacin Impurity 90 (CAS CATO-C4X-312890)
- Glycyrrhizic Acid Impurity 4 (CAS 83896-44-0)
- Mirogabalin impurity 69 (CAS CATO-C4X-292469)
- Moxifloxacin Impurity 35 (CAS 151213-39-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com