5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione CAS 246022-28-6
| CAS No. | 246022-28-6 |
| Molecular Formula | C13H9ClF3NO4 |
| Molecular Weight | 335.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 246022-28-6) is a high-purity analytical reference standard with the molecular formula C13H9ClF3NO4 and a molecular weight of 335.66 g/mol.
Structurally, 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (C13H9ClF3NO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 335.66 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9ClF3NO4 |
| Molecular Weight | 335.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-N-((perfluorophenyl)methyl)benzamide (CAS 304458-50-2)
- ethyl 1-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}-1H-1,2,3,4-tetraazole-5-carboxylate (CAS 1092346-51-4)
- 1-[4-chloro-3-(trifluoromethyl)phenyl]-5-(methoxymethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351844-81-9)
- 1-(2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine (CAS 2096341-25-0)
- 1-(3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine (CAS 2096334-57-3)
- 1-(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine (CAS 2096334-70-0)
- Ethyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-2,2-difluoroacetate (CAS 478043-86-6)
- N-(2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)cyclopentanamine (CAS 2096341-87-4)
Recommended Standards
- 2-(3-Methylpiperidin-1-yl)-N-(2,4,6-trichlorophenyl)acetamide (CAS 332162-66-0)
- 4-Chloro-2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidine (CAS 339275-97-7)
- 4-Chloro-2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidine (CAS 338955-82-1)
- 4-Chloro-2-((2,4-dichlorobenzyl)thio)-5-methoxypyrimidine (CAS 339275-84-2)
- 3-((3-Fluoro-4-nitrophenoxy)methyl)pyridine (CAS 170282-74-3)
- 1-Acetyl-5-methyl-1H-pyrazole-3-carboxylic acid (CAS 120800-48-8)
- 2-Amino-1-cycloheptylethan-1-ol (CAS 72799-59-8)
- 1,2-Didocosahexaenoyl-3-palmitoyl Glycerol (CAS 116198-44-8)
- 2-(2-(4-Chlorobenzoyl)hydrazine-1-carbonyl)benzoic acid (CAS 60580-17-8)
- 1-Cyclohexyl-3,5-dimethyl-1H-pyrazol-4-amine hydrochloride (CAS 1374407-92-7)
- 5-Fluoro-4'-methyl-[1,1'-biphenyl]-2-carbaldehyde (CAS 1537906-49-2)
- N-(3-(1H-Benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)-2,6-dichlorobenzamide (CAS 825616-48-6)
- 2-Chloro-6-(3-pyrrolidinylmethoxy)pyrazinehydrochloride (CAS 1219976-69-8)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com